Placenta
Umbilical cord
Single umbilical artery

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 18 October 2017, last major update November 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Single umbilical artery[title] "loattrfull text"[sb]

Cite this page: Ziadie, M. Single umbilical artery. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentasua.html. Accessed November 23rd, 2017.
Definition / general
  • Two vessel cord (usually are 3 vessels) with a single artery and a single vein (a hypoplastic artery may be present)
  • Remaining artery may be a persistent vitelline artery in cases of caudal regression / synringomelia
  • Diagnosed in 1% of placentas, with higher rates occurring with congenital anomalies, perinatal death and fetal growth restriction
  • Also more common in maternal diabetes
  • No increased risk of postneonatal mortality
Gross description
  • Evaluation of vessel number should be performed away from the disc due to the possibility of umbilical artery anastamoses / fusion in this location
  • Higher incidence of abnormal cord (velamentous) and membrane (circumvallate) insertion
Microscopic (histologic) images

Images hosted on other servers:

Two vessel umbilical cord