Umbilical cord
Single umbilical artery

Topic Completed: 1 November 2011

Minor changes: 20 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Single umbilical artery[title] "loattrfull text"[sb]

Mandolin S. Ziadie, M.D.
Page views in 2019: 816
Page views in 2020 to date: 358
Cite this page: Ziadie MS. Single umbilical artery. website. Accessed May 30th, 2020.
Definition / general
  • Two vessel cord (usually are 3 vessels) with a single artery and a single vein (a hypoplastic artery may be present)
  • Remaining artery may be a persistent vitelline artery in cases of caudal regression / synringomelia
  • Diagnosed in 1% of placentas, with higher rates occurring with congenital anomalies, perinatal death and fetal growth restriction
  • Also more common in maternal diabetes
  • No increased risk of postneonatal mortality
Gross description
  • Evaluation of vessel number should be performed away from the disc due to the possibility of umbilical artery anastamoses / fusion in this location
  • Higher incidence of abnormal cord (velamentous) and membrane (circumvallate) insertion
Microscopic (histologic) images

Images hosted on other servers:

Two vessel umbilical cord

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