Placental gross / microscopic abnormalities, nonneoplastic
Tenney Parker changes

Topic Completed: 1 October 2011

Minor changes: 18 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Tenney Parker

Mandolin S. Ziadie, M.D.
Page views in 2019: 1,848
Page views in 2020 to date: 795
Cite this page: Ziadie MS. Tenney Parker changes. website. Accessed June 1st, 2020.
Definition / general
  • Increased numbers of trophoblastic syncytial knots, often due to maternal hypertension or uteroplacental insufficiency
  • Often seen in association with terminal villous hypoplasia
  • Inadequate maternal perfusion (diabetes, hypertension)
Microscopic (histologic) description
  • Increased syncytial knotting
  • Changes of hypertension / preeclampsia / decidual vasculopathy may be present in the decidua
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