Placental gross / microscopic abnormalities, nonneoplastic
Tenney Parker changes

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 13 October 2017, last major update October 2011

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Tenney Parker

Cite this page: Ziadie, M. Tenney Parker changes. website. Accessed November 15th, 2018.
Definition / general
  • Increased numbers of trophoblastic syncytial knots, often due to maternal hypertension or uteroplacental insufficiency
  • Often seen in association with terminal villous hypoplasia
  • Inadequate maternal perfusion (diabetes, hypertension)
Microscopic (histologic) description
  • Increased syncytial knotting
  • Changes of hypertension / preeclampsia / decidual vasculopathy may be present in the decidua