Cite this page: Ziadie MS. Transient myeloproliferative disease of the newborn. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/placentatransientmyelo.html. Accessed September 18th, 2019.
Definition / general
- Rare leukemia-like myeloproliferative disorder associated with trisomy 21 (see chronic myeloid neoplasms chapter)
Microscopic (histologic) description
- Placenta shows villous dysmaturity with chorangiosis and prominent intravascular aggregates of primitive appearing cells with focal, early vascular wall invasion (Hum Pathol 2000;31:396)