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Placenta
Non-trophoblastic neoplasms
Transient myeloproliferative disease of the newborn
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 29 November 2011, last major update November 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
Definition
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● Rare leukemia-like myeloproliferative disorder associated with trisomy 21 (see Chronic Myeloid Neoplasms) chapter
Micro description
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● Placenta shows villous dysmaturity with chorangiosis and prominent intravascular aggregates of primitive appearing cells with focal, early vascular wall invasion (Hum Pathol 2000;31:396)
End of Placenta > Non-trophoblastic neoplasms > Transient myeloproliferative disease of the newborn
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