Placental findings in specific newborn/fetal or maternal conditions
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 27 January 2013, last major update November 2011
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Unbalanced flow of blood through arteriovenous anastomoses with worse clinical outcome if AV anastomoses without arterioarterial or venovenous anastomoses
● Results in growth discrepancy and mortality, which is usually marked in second trimester
● Both twins are at risk (70% mortality)
● After death of donor twin, may get an acute reverse transfusion
● 22 year old pregnant woman with twins, one with oligohydramnios, one with polyhydramnios (Case of Week #264)
● Serial amniocentesis; removal of a fetus
● Surgical interruption of common vasculature
● Donor twin is anemic, small and pale with small organs
● Recipient twin is large and plethoric with large organs; at risk for high-output cardiac failure
● Donor placentas have large edematous villi, small capillaries and numerous nucleated red blood cells
● Recipient placenta has small, firm and mature villi with congested vessels
End of Placenta > Placental findings in specific newborn/fetal or maternal conditions > Twin-twin transfusion
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