Adenoid basal cell tumor
Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 19 March 2012, last major update February 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Also known as adenoid cystic-like tumor, basal cell carcinoma, adenoid basal proliferation of uncertain significance
● Resembles to some extent the salivary gland tumor
● Usually indolent; cases with aggressive behavior often have large solid nests with central necrosis, high Ki67%, less staining with basal cell markers (Am J Surg Pathol 2007;31:697)
● 67 year old man (Int J Clin Oncol 2010;15:594)
● Expansive (not circumscribed) growth pattern
● Multinodular, basaloid cells in clusters, some with punched out lumens
● Surrounding fibromyxoid stroma, squamous differentiation, merges with basal cell hyperplasia
● May be associated with minor component of usual type prostatic adenocarcinoma
● Considered malignant if extensive infiltration between normal prostate gland, extension out of the prostate, perineural invasion, necrosis or metastases
● Gleason grading of these tumors is not recommended
● Arch Pathol Lab Med 1993;117:799, Am J Clin Pathol 1988;89:49
End of Prostate > Other carcinomas > Adenoid basal cell tumor
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