Prostate - Adenoid basal cell tumor

Home Chapter Home Jobs Conferences Fellowships Books

Prostate

Other carcinomas

Adenoid basal cell tumor

Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 19 March 2012, last major update February 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Also known as adenoid cystic-like tumor, basal cell carcinoma, adenoid basal proliferation of uncertain significance
● Resembles to some extent the salivary gland tumor
● Usually indolent; cases with aggressive behavior often have large solid nests with central necrosis, high Ki67%, less staining with basal cell markers (Am J Surg Pathol 2007;31:697)

Case reports
=========================================================================

● 67 year old man (Int J Clin Oncol 2010;15:594)

Micro description
=========================================================================

● Expansive (not circumscribed) growth pattern
● Multinodular, basaloid cells in clusters, some with punched out lumens
● Surrounding fibromyxoid stroma, squamous differentiation, merges with basal cell hyperplasia
● May be associated with minor component of usual type prostatic adenocarcinoma
● Considered malignant if extensive infiltration between normal prostate gland, extension out of the prostate, perineural invasion, necrosis or metastases
● Gleason grading of these tumors is not recommended

Micro images
=========================================================================

Various images

Postive stains
=========================================================================

● 34betaE12
● p63

Negative stains
=========================================================================

● PSA/PAP

Case reports
=========================================================================

● Arch Pathol Lab Med 1993;117:799, Am J Clin Pathol 1988;89:49

End of Prostate > Other carcinomas > Adenoid basal cell tumor

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).