Other carcinomas
Adenoid basal cell tumor

Authors: Komal Arora, M.D. (see Authors page)

Revised: 11 August 2016, last major update February 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: prostatic adenoid basal cell tumor
Cite this page: Adenoid basal cell tumor. website. Accessed October 28th, 2016.
Definition / General
  • Also known as adenoid cystic-like tumor, basal cell carcinoma, adenoid basal proliferation of uncertain significance
  • Resembles to some extent the salivary gland tumor
  • Usually indolent; cases with aggressive behavior often have large solid nests with central necrosis, high Ki67%, less staining with basal cell markers (Am J Surg Pathol 2007;31:697)
Case Reports
Micro Description
  • Expansive (not circumscribed) growth pattern
  • Multinodular, basaloid cells in clusters, some with punched out lumens
  • Surrounding fibromyxoid stroma, squamous differentiation, merges with basal cell hyperplasia
  • May be associated with minor component of usual type prostatic adenocarcinoma
  • Considered malignant if extensive infiltration between normal prostate gland, extension out of the prostate, perineural invasion, necrosis or metastases
  • Gleason grading of these tumors is not recommended
Micro Images

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Various images

Positive Stains
  • 34betaE12
  • p63
Negative Stains
  • PSA / PAP