Prostate gland & seminal vesicles
Other malignancies

Topic Completed: 1 October 2016

Minor changes: 27 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Angiosarcoma [title] prostate

Kenneth A. Iczkowski, M.D.
Page views in 2019: 148
Page views in 2020 to date: 93
Cite this page: Iczkowski KA. Angiosarcoma. website. Accessed August 15th, 2020.
Definition / general
  • Rare in prostate, < 20 cases reported
  • Criteria for radiation induced sarcoma: arise in area previously radiated, latent period (in years), sarcoma confirmed histologically (Cancer 1948;1:3)
Prognostic factors
  • High one year mortality
Case reports
Gross description
  • Extensive necrosis
Microscopic (histologic) description
  • Proliferative vascular channels lined by atypical, multilayered or solid endothelial cells
  • Tumor cells are pleomorphic, varying from spindled to large / plump
  • Large pleomorphic nuclei with clumped chromatin and prominent nucleoli
  • Frequent mitotic figures, some atypical
Microscopic (histologic) images

Images hosted on other servers:

Prostatic angiosarcoma

Various images

Bladder cases (no prostate involvement)

Positive stains
Negative stains
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