Prostate
Other malignancies
Angiosarcoma

Author: Kenneth Iczkowski, M.D. (see Authors page)

Revised: 17 October 2016, last major update October 2016

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Angiosarcoma [title] prostate

Cite this page: Angiosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/prostateangiosarcoma.html. Accessed October 18th, 2017.
Definition / general
  • Rare in prostate, < 20 cases reported
  • Criteria for radiation induced sarcoma: arise in area previously radiated, latent period (in years), sarcoma confirmed histologically (Cancer 1948;1:3)
Etiology
Prognostic factors
  • High one year mortality
Case reports
Gross description
  • Extensive necrosis
Microscopic (histologic) description
  • Proliferative vascular channels lined by atypical, multilayered or solid endothelial cells
  • Tumor cells are pleomorphic, varying from spindled to large / plump
  • Large pleomorphic nuclei with clumped chromatin and prominent nucleoli
  • Frequent mitotic figures, some atypical
Microscopic (histologic) images

Images hosted on other servers:

Prostatic angiosarcoma

Various images

Bladder cases (no prostate involvement)

Positive stains
Negative stains