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Prostate

Microscopic mimics of prostatic carcinoma

Atrophy

Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 3 May 2012, last major update May 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Common finding; increases with age; not premalignant (Mod Pathol 1998;11:47)
● Diffuse or focal; can be subtyped further (Int Braz J Urol 2010;36:401)
● Benign mimic of adenocarcinoma (Am J Surg Pathol 2008;32:851)
● More frequent in peripheral zone

Micro description
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● Glands arranged in multiple lobules separated by fibrotic stroma
● Have well-formed open lumens, scant cytoplasm, hyperchromatic nuclei, small/inconspicuous nucleoli
● Basal layer present but may be fragmented

Micro images
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Various images

   
34βE12

   
Partial atrophy

   
Simple atrophy

   
Sclerotic atrophy

End of Prostate > Microscopic mimics of prostatic carcinoma > Atrophy

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