Prostate
Benign lesions / conditions
Calculi

Authors: Komal Arora, M.D. (see Authors page)

Revised: 21 July 2016, last major update March 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: prostatic calculi
Definition / General
  • Rare in children, infrequent < age 40, common > age 50
  • May be solitary but usually occur in clusters and are associated with nodular hyperplasia, prostatic carcinoma, metabolic abnormalities or other abnormalities (Prostate 1985;7:91)
  • Identified in 7% of prostates with nodular hyperplasia
  • Stones usually contain phosphate salts of calcium, magnesium, potassium, calcium carbonate or calcium oxalate; stones in enlarged prostatic utricles contain hydroxyapatite (J Androl 2012;33:45)
  • Corpora amylacea may act as nidus for stone formation
  • Radioopaque, are detected by Xray
  • Rarely are infected and cause abscesses
Treatment
  • Prostatectomy may be required for large calculi
Gross Description
  • Brown-gray, round-ovoid, usually smooth surface
Gross Images

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Prostate stones

Micro Description
  • Stratified in concentric layers resembling calcified corpora amylacea
Differential Diagnosis
  • Carcinoma (clinically both are hard), calculi from bladder, ureter or renal pelvis lodging in prostatic urethra