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Benign lesions/conditions


Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 13 April 2012, last major update March 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Rare in children, infrequent < age 40, common > age 50
● May be solitary but usually occur in clusters and are associated with nodular hyperplasia, prostatic carcinoma, metabolic abnormalities or other abnormalities (Prostate 1985;7:91)
● Identified in 7% of prostates with nodular hyperplasia
● Stones usually contain phosphate salts of calcium, magnesium, potassium, calcium carbonate or calcium oxalate; stones in enlarged prostatic utricles contain hydroxyapatite (J Androl 2012;33:45)
● Corpora amylacea may act as nidus for stone formation
● Radioopaque, are detected by Xray
● Rarely are infected and cause abscesses


● Prostatectomy may be required for large calculi

Gross description

● Brown-gray, round-ovoid, usually smooth surface

Gross images

Prostate stones

Micro description

● Stratified in concentric layers resembling calcified corpora amylacea

Differential diagnosis

● Carcinoma (clinically both are hard), calculi from bladder, ureter or renal pelvis lodging in prostatic urethra

End of Prostate > Benign lesions/conditions > Calculi

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