Prostate
Prostatic carcinoma
Immunohistochemistry

Author: Kenneth Iczkowski, M.D. (see Authors page)

Revised: 15 August 2016, last major update April 2015

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: Immunohistochemistry [title] prostate

Related: CK903 / cytokeratin 34βE12 / high molecular weight cytokeratin, p63, AMACR / P504S, Prostate specific antigen (PSA) / Prostatic acid phosphatase (PAP) , Prostate cancer vs. ASAP vs. Benign, Prostate vs. Urothelial carcinoma

Cite this page: Immunohistochemistry. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/prostateihc.html. Accessed December 5th, 2016.
Definition / General
Terminology
  • The two main types of immunostains for workup of minute foci of carcinoma or suspicious for carcinoma are a basal cell immunostain cocktail (consisting of cytoplasmic marker cytokeratin 34βE12, also called cytokeratin 903, plus nuclear marker p63), and alpha-methylacyl CoA racemase (AMACR, P504S)
  • These are often used together in a cocktail as a "triple stain"
  • See related topics for their characteristics