Prostate
Prostatic carcinoma
Immunohistochemistry


Topic Completed: 1 April 2015

Revised: 26 February 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Immunohistochemistry [title] prostate

Related: CK903 / cytokeratin 34βE12 / high molecular weight cytokeratin, p63, AMACR / P504S, Prostate specific antigen (PSA) / Prostatic acid phosphatase (PAP), Prostate cancer vs. ASAP vs. Benign, Prostate vs. Urothelial carcinoma
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Cite this page: Iczkowski KA. Immunohistochemistry. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/prostateihc.html. Accessed March 21st, 2019.
Definition / general
Terminology
  • The two main types of immunostains for workup of minute foci of carcinoma or suspicious for carcinoma are a basal cell immunostain cocktail (consisting of cytoplasmic marker cytokeratin 34βE12, also called cytokeratin 903, plus nuclear marker p63), and alpha-methylacyl CoA racemase (AMACR, P504S)
  • These are often used together in a cocktail as a "triple stain"
  • See related topics for their characteristics
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