Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 21 July 2012, last major update July 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Also called pseudosarcomatous fibromyxoid tumor, inflammatory myofibroblastic tumor
● Similar to postoperative spindle cell nodule but without history of TURP
● Rare, resembles sarcoma or sarcomatoid carcinoma (Hum Pathol 1993;24:1203)
● Diploid, low S phase fraction
● Benign behavior
● 42 year old man with bladder mass extending into prostate (Urol Int 1996;57:249)
● 61 year old man (ScientificWorldJournal 2011;11:1027)
● Myxoid lesions, proliferation of slightly atypical spindle fibroblastic cells in a background of granulation tissue-type vascularity and inflammatory cells
● Rare mitoses, no atypical mitoses
● Vimentin, smooth muscle actin, CD68 (in histiocytes)
● S100, desmin, myoglobin, keratin
● Fibroblastic and myofibroblastic cell features
End of Prostate > Benign lesions/conditions > Inflammatory pseudotumor
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