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Prostate

Benign lesions/conditions

Inflammatory pseudotumor


Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 21 July 2012, last major update July 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Also called pseudosarcomatous fibromyxoid tumor, inflammatory myofibroblastic tumor
● Similar to postoperative spindle cell nodule but without history of TURP
● Rare, resembles sarcoma or sarcomatoid carcinoma (Hum Pathol 1993;24:1203)
● Diploid, low S phase fraction
● Benign behavior

Case reports
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● 42 year old man with bladder mass extending into prostate (Urol Int 1996;57:249)
● 61 year old man (ScientificWorldJournal 2011;11:1027)

Micro description
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● Myxoid lesions, proliferation of slightly atypical spindle fibroblastic cells in a background of granulation tissue-type vascularity and inflammatory cells
● Rare mitoses, no atypical mitoses

Micro images
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Various images

Positive stains
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● Vimentin, smooth muscle actin, CD68 (in histiocytes)

Negative stains
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● S100, desmin, myoglobin, keratin

Electron microscopy
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● Fibroblastic and myofibroblastic cell features

End of Prostate > Benign lesions/conditions > Inflammatory pseudotumor


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