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Prostate

Other malignancies

Lymphoma

Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 8 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● 10% of non-Hodgkin’s lymphomas and 10% of leukemias (20% of CLL) involve the prostate
● Approximately 1% of pelvic lymph nodes removed at prostatectomy demonstrate demonstrate malignancy, usually SLL
● Often no other signs/symptoms
● Associated with acute urinary obstruction (Cancer 1998;83:732)
● Rarely is initial site for Hodgkin’s lymphoma or angiotropic lymphoma
● SLL may be incidentally identified in pelvic lymph nodes (Arch Pathol Lab Med 2003;127:567, Am J Hematol 2011;86:952, Cancer 1998;83:732)

Case reports
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● 29 year old man with diffuse large B cell lymphoma (Int Braz J Urol 2006;32:64)
● 67 year old man with coexisting MALT lymphoma and prostatic adenocarcinoma (Rare Tumors 2010;2:e54)
● 82 year old man with mantle cell lymphoma (Can Urol Assoc J 2009;3:E94)

Treatment (SLL)
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● Radiation therapy for symptoms

Gross (SLL)
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● Enlarged nodes (mean 3.2 cm)

Micro description (SLL)
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● Diffuse architectural effacement, replacement of sinuses by tumor cells, pseudofollicles usually present, lack of cortical follicles

Micro images
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Diffuse large B cell lymphoma: H&E and CD20

   
MALT lymphoma

   
Mantle cell lymphoma

   
SLL and other disorders

End of Prostate > Other malignancies > Lymphoma

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