Benign lesions / conditions
Paneth cell-like change

Authors: Monika Roychowdhury, M.D. (see Authors page)

Revised: 28 July 2016, last major update July 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: prostatic Paneth cell-like change
Cite this page: Paneth cell-like change. website. Accessed April 26th, 2018.
Definition / general
Virtual slides

Images hosted on other servers:

Adenocarcinoma of prostate with Paneth
cell-like neuroendocrine differentiation

Positive stains
  • PAS+ diastase resistant (benign epithelium), neuroendocrine markers (dysplastic / malignant epithelium), PSA
Negative stains
  • Lysozyme
Electron microscopy description
  • Exocrine-like or lysosomal-like vesicles in benign epithelium, neuroendocrine granules in dysplastic / malignant epithelium