Benign lesions / conditions
Paneth cell-like change

Authors: Monika Roychowdhury, M.D. (see Authors page)

Revised: 28 July 2016, last major update July 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: prostatic Paneth cell-like change
Cite this page: Paneth cell-like change. website. Accessed April 26th, 2017.
Definition / General
Virtual Slides

Images hosted on other servers:

Adenocarcinoma of prostate with Paneth
cell-like neuroendocrine differentiation

Positive Stains
  • PAS+ diastase resistant (benign epithelium), neuroendocrine markers (dysplastic / malignant epithelium), PSA
Negative Stains
  • Lysozyme
Electron Microscopy Description
  • Exocrine-like or lysosomal-like vesicles in benign epithelium, neuroendocrine granules in dysplastic / malignant epithelium