Prostate gland & seminal vesicles
Benign lesions/conditions
Postoperative spindle cell nodule

Topic Completed: 1 July 2012

Minor changes: 9 January 2020

Copyright: 2003-2020,, Inc.

PubMed search: prostatic postoperative spindle cell nodules

Monika Roychowdhury, M.D.
Page views in 2019: 546
Page views in 2020 to date: 336
Cite this page: Roychowdhury M. Postoperative spindle cell nodule. website. Accessed August 7th, 2020.
Definition / general
Gross description
  • Friable red nodules, resembling granulation tissue or sarcoma
Microscopic (histologic) description
  • Cellular with high mitotic activity
  • Intersecting fascicles of spindle cells with extravasated red blood cells resembling Kaposi‚Äôs sarcoma
  • Minimal nuclear pleomorphism, no atypical mitoses
  • Relatively small size
Microscopic (histologic) images

AFIP images

Bladder tumors (similar histology)

Positive stains
  • Keratin (strong), actin (variable)
Negative stains
  • EMA
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