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Granulomatous lesions

Post-TURP granulomatous prostatitis

Reviewers: Ali Amin, M.D., (see Reviewers page)
Revised: 7 January 2012, last major update January 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Formerly called eosinophilic prostatitis

Clinical features

● No systemic symptoms
● Develop months after an invasive procedure as a reaction to the procedure and tissue damage (most commonly following TURP, less commonly after biopsy or cautery)

Hair granuloma:
● Post-TURP; hair is probably embedded in prostate by earlier needle biopsy (Hum Pathol 1996;27:196)

Micro description

● Central region of fibrinoid necrosis surrounded by pallisading histiocytes
● Resembles rheumatoid nodules
● Long tortuous granulomas may dissect tissue
● Minimal surrounding inflammation (lymphocytes, plasma cells, rare eosinophils)
● More eosinophils in first month after TURP (Am J Surg Pathol 1984;8:217)

Micro images

Post-biopsy granuloma

End of Prostate > Granulomatous lesions > Post-TURP granulomatous prostatitis

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