Prostate gland & seminal vesicles
Prostatitis with eosinophils

Topic Completed: 1 June 2016

Minor changes: 25 February 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Prostatitis with eosinophils

Kenneth A. Iczkowski, M.D.
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Table of Contents
Differential diagnosis
Cite this page: Iczkowski KA. Prostatitis with eosinophils. website. Accessed August 14th, 2020.
Differential diagnosis
Four possibilities should be considered:

  • Post-surgical granulomatous prostatitis can be seen after transurethral resection (Med Mol Morphol 2007;40:29)
    • In this situation, there would also be granulomas with palisading histiocytes, with or without necrosis

  • Churg-Strauss syndrome can cause an allergic granulomatous prostatitis
    • Typically such patients have a history of asthma or allergy with peripheral eosinophilia and systemic afflictions
    • Prostate shows granulomas with fibrinoid necrosis and vasculitis (Int J Urol 2006;13:838)

  • Recently, eosinophilic prostatitis has been described in nine cases of men with autoimmune pancreatitis and IgG4 associated cholangitis (Urology 2014;83:521)
    • These patients had urine retention, lymphoplasmacytic infiltrate of the prostate with eosinophils, and up to 150 IgG4 positive cells per high power field

  • Rarely, eosinophils in the prostate may be due to parasites
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