Seminal vesicles

Authors: Komal Arora, M.D. (see Authors page)

Revised: 7 September 2016, last major update July 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: prostatic seminal vesicle amyloidosis

Cite this page: Amyloidosis. website. Accessed October 17th, 2018.
Definition / general
  • Although immunohistochemistry often detects lactoferrin (Ann Pathol 2004;24:236), amyloid apparently derives from semenogelin I, the major secretory product of the seminal vesicles (J Lab Clin Med 2005;145:187)
  • Semenogelin I and II are mainly responsible for immediate gel formation of freshly ejaculated semen, and are degraded by the proteolytic action of prostate specific antigen/PSA (J Androl 1996;17:17)
Case reports
Microscopic (histologic) images
Images hosted on PathOut server:

66 year old man with radical prostatectomy for adenocarcinoma

Trichrome stain

Positive stains
Electron microscopy description