Prostate
Seminal vesicles
Amyloidosis

Authors: Komal Arora, M.D. (see Authors page)

Revised: 7 September 2016, last major update July 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: prostatic seminal vesicle amyloidosis

Definition / General
Etiology
  • Although immunohistochemistry often detects lactoferrin (Ann Pathol 2004;24:236), amyloid apparently derives from semenogelin I, the major secretory product of the seminal vesicles (J Lab Clin Med 2005;145:187)
  • Semenogelin I and II are mainly responsible for immediate gel formation of freshly ejaculated semen, and are degraded by the proteolytic action of prostate specific antigen/PSA (J Androl 1996;17:17)
Case Reports
Micro Images
Images hosted on PathOut server:

66 year old man with radical prostatectomy for adenocarcinoma



Trichrome stain



Positive Stains
Electron Microscopy Description