Seminal vesicles

Authors: Komal Arora, M.D. (see Authors page)

Revised: 8 September 2016, last major update July 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: prostatic seminal vesicle carcinoma

Cite this page: Carcinoma. website. Accessed October 17th, 2018.
Definition / general
  • Very rare, must confirm microscopically
  • Primary tumors should be localized primarily to seminal vesicle; must rule out invasion from prostate (do PSA / PAP), rectum or other sites
  • Usually a papillary adenocarcinoma resembling architecture of normal seminal vesicle
  • Resembles prostatic duct adenocarcinoma Gleason patterns 3 or 4 or mucinous (colloid) carcinoma
  • Usually unresectable and patients die within 2 years
  • Adenocarcinoma: very rare, must rule out prostate primary; often mucin producing, ulcerates through skin of scrotum
Case reports
Gross images
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Low grade epithelial stromal tumor

Microscopic (histologic) images
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Metastatic hepatocellular carcinoma

Low grade epithelial stromal tumor

Positive stains
Negative stains
Differential diagnosis