Prostate - Solitary fibrous tumor

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Prostate

Other malignancies

Solitary fibrous tumor

Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 9 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Rare (< 50 cases reported)
● Often misdiagnosed
● Usually does not recur after excision (Hum Pathol 2000;31:63), but some cases have malignant behavior

Case reports
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● 60 year old man (Case Rep Oncol 2012;5:22)

Micro description
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● Collagenization, hemangiopericytoma-like foci, spindled cells between strips of collagen
● Two cases described were
● (a) well circumscribed, minimal mitotic activity or pleomorphism and
● (b) cellular, less collagenous, more diffuse growth pattern, cytologic atypia, high mitotic activity (Arch Pathol Lab Med 2001;125:274)

Micro images
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Various images

Positive stains
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● CD34, bcl2

Differential diagnosis
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● Other spindle cell neoplasms of the prostate
● Gastrointestinal stromal tumors that may arise from the rectal wall with invasion of the prostate or from the region between the rectum and the prostate (Am J Surg Pathol 2007;31:870)

Additional references
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● Eur Urol 2009;56:564

End of Prostate > Other malignancies > Solitary fibrous tumor

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