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Prostate
Other malignancies
Synovial sarcoma
Reviewers: Komal Arora, M.D., (see Reviewers page)
Revised: 21 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
See also Soft Tissue Tumor chapter
Case reports
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● 37 year old man with monophasic tumor (Am J Surg Pathol 1999;23:220)
Gross images
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Heterogeneously grey white tumor
Micro description
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● Uniform spindle and oval cells forming interlacing fascicles resembling fibrosarcoma
● Focally the compact fascicles of tumor cells alternate with hypocellular myxoid tissue resembling peripheral nerve sheath tumors, focal pericytomatous pattern of polygonal cells arranged around dilated, thin-walled blood vessels
Micro images
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Positive stains
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● Vimentin (most cells), EMA (focal)
Negative stains
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● S100, keratin, neuron-specific enolase, CD34, desmin, muscle-specific actin, alpha-smooth muscle actin
Molecular description
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● t(X;18)(p11.2;q11.2) (Int J Surg Pathol 2008;16:329)
End of Prostate > Other malignancies > Synovial sarcoma
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