Salivary glands
Nonneoplastic tumors and tumor-like conditions
Adenomatous ductal hyperplasia of major / minor salivary glands


Topic Completed: 1 October 2015

Revised: 20 March 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Adenomatous ductal hyperplasia
Page views in 2018: 1,202
Page views in 2019 to date: 459
Cite this page: Tanakchi S Adenomatous ductal hyperplasia of major / minor salivary glands. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandsADH.html. Accessed April 25th, 2019.
Definition / general
  • Incidental microscopic finding (70% incidence) during histologic examination of a salivary gland tumor
  • Predominates in male patients (3:1) in sixth decade of life
  • More frequent in parotid compared to submandibular gland (3:1)
  • Hypothesized to be a precursor lesion of salivary gland tumor, especially epithelial myoepithelial carcinoma
Microscopic (histologic) description
  • Proliferating ducts admixed with acinar cell complexes
  • Ducts are frequently lined with single layer of cells; on occasion, may have luminal and abluminal lining cells
  • Acinar cells are characterized by atrophic changes (loss of zymogen granules, decrease in cell volume) resulting in morphologic resemblance to intercalated ducts
Additional references
Back to top