Salivary glands
Cytopathology competency / milestone assessment
3. Cells

Authors: Michelle R. Pramick, M.D., Zubair W. Baloch, M.D., Ph.D. (see Authors page)

Revised: 9 March 2018, last major update December 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Salivary gland cells[TIAB] cytopathology

Cite this page: Pramick, M.R., Baloch, Z.W. Cytopathology competency - 3. cells. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandscompthecells.html. Accessed July 21st, 2018.
Acinic cells
Medical knowledge:
  1. Recognize the architectural arrangement and key nuclear and cytoplasmic features of various forms of acinic cells
  2. Understand the function of the acinic cell secretions

Practice based learning:
  1. Know that mucinous acinic cells produce acid sialomucins (Alcian blue and mucicarmine positive) and neutral sialomucins (PAS positive)
Ductal cells
Medical knowledge:
  1. Recognize the architectural arrangement and key nuclear and cytoplasmic features of ductal cells
Myoepithelial cells
Medical knowledge:
  1. Recognize the architectural arrangement and key nuclear and cytoplasmic features of myoepithelial cells
  2. Understand the function of myoepithelial cells
Oncocytes
Medical knowledge:
  1. Recognize the architectural arrangement and key nuclear and cytoplasmic features of oncocytes
  2. Know that oncocytes appear with age in the normal salivary gland and some lobules as they undergo focal oncocytic metaplasia
  3. Understand that oncocytic metaplasia begins in the patients forties
Miscellaneous
Medical knowledge:
  1. Understand that adipose tissue is normal in the salivary gland and that it increases with age and may be massive in alcoholic or malnourished patients
  2. Recognize that ciliated respiratory type glandular cells can occasionally be seen in salivary gland ducts
  3. Recognize that the parotid gland may have sebaceous cells
  4. Understand that squamous metaplasia can occur due to chronic inflammation, ischemia, radiation or neoplasia
  5. Know that psammoma bodies are seen in a variety of benign and neoplastic conditions and are nonspecific
  6. Know that crystals of various types can be identified in salivary gland aspirate biopsies
    • Tyrosine rich and collagen rich crystals in pleomorphic adenoma
    • Sulfur rich crystals in cysts
    • Alpha amylase rich crystals in sialadenitis
Lymphoid tissue
Medical knowledge:
  1. Recognize the architectural arrangement and key nuclear and cytoplasmic features of lymphocytes
  2. Understand that lymphoid tissue may be aspirated from intraparotid or adjacent cervical lymph nodes