Salivary glands
Other tumors

Author: Adriana Handra-Luca, M.D. (see Authors page)

Revised: 21 March 2018, last major update September 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Embryoma salivary

Cite this page: Handra-Luca, A. Embryoma. website. Accessed April 22nd, 2018.
Definition / general
Clinical features
  • Childhood epithelial salivary gland tumor; common among the perinatal tumors
  • Occurs in submandibular, parotid or minor salivary glands; also ectopic salivary gland tissue
  • Uni or multinodular, 2 - 7 cm, rapid growth
  • May recur locally or involve regional lymph nodes; also lung metastases
Case reports
Microscopic (histologic) description
  • Ductules and solid organoid nests of basaloid cells with fine chromatin and cuboidal epithelial cells
  • 2 histological patterns: favorable pattern with semiencapsulation of benign basaloid cells with intervening stroma; unfavorable pattern with anaplastic basaloid cells, broad pushing to infiltrative periphery and minimal stroma (Ann Diagn Pathol 2006;10:320)
  • Variable necrosis, variable mitotic activity, variable nuclear atypia, no perineurial invasion
Microscopic (histologic) images

Images hosted on other servers:

One year old boy with parotid tumor

Recurrent and metastatic tumor

Nests of basaloid cells
with poorly demarcated
eosinophilic cytoplasm
and round, vesicular nuclei

Cytology description
  • Tight, solid clusters of atypical basaloid cells plus dispersed epithelial and myoepithelial cells with metachromatic magenta hyaline globular material
Positive stains
Differential diagnosis