Salivary glands
Non-neoplastic tumors and tumor-like conditions
Epidermoid cyst

Author: Sally Tanakchi, M.B.Ch.B. (see Authors page)
Editor: F. Zahra Aly, M.D., Ph.D.

Revised: 30 October 2015, last major update October 2015

Copyright: (c) 2002-2015,, Inc.

PubMed Search: Epidermoid cyst [title] salivary
Definition / General
  • Very rare in salivary glands with few reports of involvement of major salivary glands
  • Histogenesis thought to be ectodermal, and derived from remnants of branchial pouch epithelium
  • Since easily mistaken for salivary gland abscess, neoplasm or other cysts, excision required for diagnosis and treatment
Case Reports
Clinical Images
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No surface discharge

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Mobility in teeth

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Salivary gland swelling

Gross Images
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Globular mass

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Parotidectomy specimen

Micro Description
  • Unilocular cyst with squamous lining containing a granular layer, usually filled with cheesy material or keratin
Micro Images
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Stratified squamous epithelium

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Mature squamous cells

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Parotid acini