Salivary glands
Epithelial / myoepithelial tumors
Inflammatory myofibroblastic tumor

Author: Adriana Handra-Luca, M.D. (see Authors page)

Revised: 14 March 2018, last major update September 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Inflammatory myofibroblastic tumor salivary

Cite this page: Handra-Luca, A. Inflammatory myofibroblastic tumor. website. Accessed December 13th, 2018.
Definition / general
  • Uncommon salivary gland tumor of myofibroblasts and chronic inflammatory cells; benign behavior at this site
  • Some cases are neoplastic
  • Also called inflammatory pseudotumor; formerly called plasma cell granuloma
  • Usually > 50 years, males
  • Parotid gland most common salivary gland site
Clinical features
  • Recurrent painful swelling
Case reports
  • Surgical resection
Gross description
  • Firm nodules, homogeneous yellow-gray
Microscopic (histologic) description
Microscopic (histologic) images

Images hosted on other servers:

Multinodular tumor with thick fibrous bands, plasma cells, lymphocytes, spindle cells in poorly formed fascicles, smooth muscle actin+

Various images

Cytology description
  • Groups of spindle cells without cytologic atypia, inflammatory cells, foamy histiocytes (Acta Cytol 2004;48:574)
Differential diagnosis