Salivary glands - Inverted ductal papilloma

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Salivary glands

Epithelial / myoepithelial tumors

Inverted ductal papilloma

Reviewer: Adriana Handra-Luca, M.D. (see Reviewers page)
Revised: 27 January 2013, last major update September 2012
Copyright: (c) 2003-2013, Pathol2gyOutlines.com, Inc.

General
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● Benign tumor of minor salivary glands, parotid which resembles inverted papilloma of nasal cavity
● Derives from proximal salivary gland excretory duct (Cancer 1982;49:519)
● Usually adults (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;92:68), no gender preference

Case reports
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● 49 year old man with mass in buccal mucosa of mandible (Pathol Int 2006;56:457)

Treatment
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● Resection, does not recur

Gross description
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● Small submucosal mass

Micro description
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● Complex invaginations of well differentiated squamous or basaloid epithelium with microcysts, mucous cells including goblet cells, columnar lining cells

Micro images
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Inverted papilloma of head & neck, not salivary glands

Positive stains
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● CK13, CK14; less strong for CK8, CK18

End of Salivary glands > Epithelial / myoepithelial tumors > Inverted ductal papilloma

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