Salivary glands
Epithelial / myoepithelial tumors

Author: Adriana Handra-Luca, M.D. (see Authors page)

Revised: 14 March 2018, last major update September 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Lipoadenoma salivary

Page views in 2018: 274
Page views in 2019 to date: 14
Cite this page: Handra-Luca, A. Lipoadenoma. website. Accessed January 19th, 2019.
Definition / general
  • Slow growing tumor with glandular structures with sertoliform features and adipose tissue; oncocytic and sebaceous differentiation
  • Initially described by Yau in 1997 (Mod Pathol 1997;10:242)
Clinical features
  • Usually men; affects parotid, submandibular glands
  • May derive from striated duct
Case reports
  • Complete excision
Microscopic (histologic) description
  • Mature adipose cells (> 90% mass) and proliferated glandular tissue (sharply demarcated, duct - acinar units or proliferated glands, may resemble sertoliform tubules), oncocytic change, sebaceous differentiation, squamous metaplasia
Microscopic (histologic) images

Images hosted on other servers:

Various images

Cytology description
  • Adipocytic background, oncocytic cells; resembles oncocytoma, acinic cell carcinoma with oncocytic change (Acta Cytol 2009;53:437)
Molecular / cytogenetics description
  • t(12,14) / HMGA rearrangements