Salivary glands
Other tumors
Lipoma / lipoadenoma

Topic Completed: 1 September 2012

Revised: 1 May 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Lipoma[TI] OR lipoadenoma[TI] salivary

Adriana Handra-Luca, M.D.
Page views in 2019: 626
Page views in 2020 to date: 53
Cite this page: Handra-Luca A. Lipoma / lipoadenoma. website. Accessed January 28th, 2020.
Definition / general
Clinical features
  • 3% of parotid tumors - #2 most common benign mesenchymal neoplasms of major salivary glands (#1 is schwannoma)
  • Often incidental (Rev Stomatol Chir Maxillofac 1988;89:117)
  • Ages 40+, usually men, occasionally children
Case reports
Microscopic (histologic) description
  • Lipoma: bland appearing adipose tissue; osteolipoma or angiolipoma variants exist
  • Lipoadenoma: mature adipose cells (> 90% mass) and proliferated glandular tissue (sharply demarcated, duct - acinar units or proliferated glands, may resemble sertoliform tubules), oncocytic change, sebaceous differentiation, squamous metaplasia
Microscopic (histologic) images

Images hosted on other servers:

Spindle cell lipoma of parotid gland

Pleomorphic lipoma with classic floret-like cells

Chondroid lipoma
of lip has chondroid
and lipomatous

Oncocytic lipoadenoma of parotid

Cytology description
Cytology images

Images hosted on other servers:

Spindle cell lipoma:
bland spindle cells
with myxoid change
and fat, CD34+

Molecular / cytogenetics description
  • t(12,14) / HMGA rearrangements
Differential diagnosis
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