Reviewer: Adriana Handra-Luca, M.D. (see Reviewers page)
Revised: 27 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Diffuse deposition of adipose tissue (usually throughout parotid gland) with overall enlargement of gland but no distinct mass
● Associated with alcoholism, cirrhosis, diabetes, hormonal abnormalities, malnutrition
● May be preceded by sialadenosis (acinar cell hypertrophy, interstitial edema, ductal atrophy)
● Slow growing, usually in parotid gland, may affect children
● May recur
● 5 month old girl with rapidly progressive parotid lipomatosis (Saudi Med J 2003;24:898)
● 9 year old boy (Int J Clin Pract 2009;63:335)
● 38 year old man with myoepithelioma of minor palatinal salivary glands with extensive lipomatosis (Laryngorhinootologie 2005;84:432)
● 47 year old man with well circumscribed 3 cm parotid nodule (Ann Pathol 2002;22:219)
● Slow growing parotid mass (J Pediatr Surg 1996;31:1422)
In parotid gland of HIV+ man
● Myoepithelioma: some cases have coexisting lipomatosis
● Pleomorphic adenoma: some cases have lipometaplasia or lipomatous foci (Am J Surg Pathol 2005;29:1389)
End of Salivary glands > Other tumors > Lipomatosis
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