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Salivary glands

Other tumors

Lipomatosis


Reviewer: Adriana Handra-Luca, M.D. (see Reviewers page)
Revised: 27 January 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Diffuse deposition of adipose tissue (usually throughout parotid gland) with overall enlargement of gland but no distinct mass
● Associated with alcoholism, cirrhosis, diabetes, hormonal abnormalities, malnutrition
● May be preceded by sialadenosis (acinar cell hypertrophy, interstitial edema, ductal atrophy)
● Slow growing, usually in parotid gland, may affect children
● May recur

Case reports
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● 5 month old girl with rapidly progressive parotid lipomatosis (Saudi Med J 2003;24:898)
● 9 year old boy (Int J Clin Pract 2009;63:335)
● 38 year old man with myoepithelioma of minor palatinal salivary glands with extensive lipomatosis (Laryngorhinootologie 2005;84:432)
● 47 year old man with well circumscribed 3 cm parotid nodule (Ann Pathol 2002;22:219)
● Slow growing parotid mass (J Pediatr Surg 1996;31:1422)

Micro images
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In parotid gland of HIV+ man

Differential diagnosis
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Myoepithelioma: some cases have coexisting lipomatosis
Pleomorphic adenoma: some cases have lipometaplasia or lipomatous foci (Am J Surg Pathol 2005;29:1389)

End of Salivary glands > Other tumors > Lipomatosis


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