Salivary glands
Epithelial / myoepithelial tumors
Oncocytosis

Author: Adriana Handra-Luca, M.D. (see Authors page)

Revised: 16 March 2018, last major update September 2012

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PubMed Search: Oncocytosis salivary

Cite this page: Handra-Luca, A. Oncocytosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandsoncocytosis.html. Accessed October 17th, 2018.
Definition / general
  • Either parotid cysts lined by oncocytes or well defined clusters of oncocytes (mm to cm)
  • First reported by Schwartz (Cancer 1969;23:636)
  • Also called multinodular oncocytoma, multifocal adenomatous oncocytic hyperplasia
Clinical features
  • Benign, multifocal / nodular or diffuse proliferation of oncocytic cells, usually in parotid gland
  • May be bilateral
Case reports
Microscopic (histologic) description
  • Either parotid cysts lined by oncocytes or well defined clusters of oncocytes (mm to cm)
  • Oncocytes (oxyphilic cells) are large ductal epithelial cells with eosinophilic granular cytoplasm
Microscopic (histologic) images

Images hosted on other servers:

Parotid gland specimen

Cytology description
  • Oncocytic cells
Cytology images

Images hosted on other servers:

Various images

Electron microscopy description
  • Numerous mitochondria
Differential diagnosis