Salivary glands
Nonneoplastic tumors/tumor-like conditions
Oncocytosis


Topic Completed: 1 September 2012

Revised: 17 May 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Oncocytosis salivary

Adriana Handra-Luca, M.D.
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Cite this page: Handra-Luca A. Oncocytosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandsoncocytosis.html. Accessed October 19th, 2019.
Definition / general
  • Either parotid cysts lined by oncocytes or well defined clusters of oncocytes (mm to cm)
  • First reported by Schwartz (Cancer 1969;23:636)
  • Also called multinodular oncocytoma, multifocal adenomatous oncocytic hyperplasia
Clinical features
  • Benign, multifocal / nodular or diffuse proliferation of oncocytic cells, usually in parotid gland
  • May be bilateral
Case reports
Microscopic (histologic) description
  • Either parotid cysts lined by oncocytes or well defined clusters of oncocytes (mm to cm)
  • Oncocytes (oxyphilic cells) are large ductal epithelial cells with eosinophilic granular cytoplasm
Microscopic (histologic) images

Images hosted on other servers:

Parotid gland specimen

Cytology description
  • Oncocytic cells
Cytology images

Images hosted on other servers:

Various images

Electron microscopy description
  • Numerous mitochondria
Differential diagnosis
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