Salivary glands
Primary salivary gland neoplasms - malignant
Papillary adenocarcinoma


Topic Completed: 1 September 2012

Revised: 30 April 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Papillary adenocarcinoma[TIAB] salivary

Adriana Handra-Luca, M.D.
Page views in 2018: 935
Page views in 2019 to date: 853
Cite this page: Handra-Luca A. Papillary adenocarcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandspapillaryadenocarcinoma.html. Accessed October 22nd, 2019.
Definition / general
  • Rare tumor of well defined papillary structures, usually mucin, no squamous or intermediate cell components; call papillary cystadenocarcinoma if prominent cystic component
Clinical features
Case reports
Gross description
  • Often large, with hemorrhage and necrosis
Microscopic (histologic) description
  • Well defined papillary structures, usually mucin, no squamous or intermediate cell components (Am J Surg Pathol 1984;8:367)
  • May appear as focal malignant component in otherwise benign mucinous cystadenoma; may occur in malignant mixed tumor associated with myoepithelial carcinoma (Ann Plast Surg 1997;39:656)
Microscopic (histologic) images

Images hosted on other servers:


51 year old man with low grade tumor with metastases


PLUNC protein expression

Positive stains
Molecular / cytogenetics description
Differential diagnosis
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