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Salivary glands

Developmental disorders

Polycystic disease

Reviewers: Fatima Aly, M.D., National Cancer Institute (see Reviewers page)
Revised: 7 October 2011, last major update August 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

General
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● Least common of the benign cystic lesions of the parotid gland.
● Also called dysgenetic disease
● Clinically characterized by recurrent, painless swelling of the involved gland(s) which are not associated with any other abnormality
● Not clear whether this is associated with cystic conditions of the kidney, liver, lung or pancreas
● Developmental disorder of mainly females with mainly bilateral gland enlargement

Micro description
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● Classically shows distended lobules composed of epithelial lined cysts imparting a honeycombed or lattice like appearance
● Cystic spaces contain eosinophilic material and eosinophilic bodies with concentric and radial patterns
● No associated inflammatory reaction
● The origin of the cyst epithelium is thought to be from the intercalated duct
● Residual islands of salivary glands may be interspersed between the cysts

End of Salivary Glands > Developmental disorders > Polycystic disease

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