Salivary glands
Other tumors
Sialolipoma


Topic Completed: 1 September 2012

Revised: 25 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Sialolipoma salivary

Adriana Handra-Luca, M.D.
Page views in 2018: 719
Page views in 2019 to date: 630
Cite this page: Handra-Luca A Sialolipoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandssialolipoma.html. Accessed August 20th, 2019.
Definition / general
  • Uncommon lipoma variant composed of mature adipose tissue mixed with acinar, ductal, basal and myoepithelial cells of normal salivary gland
  • First described in 2001 by Nagao (Histopathology 2001;38:30)
Clinical features
  • Mean age 61 years but wide age range at presentation
  • Female gender predominance for minor salivary gland location
  • Parotid and submandibular glands, hard and soft palate
  • May be due to entrapment of salivary gland elements by lipoma
  • Benign behavior, no recurrences reported
Case reports
Treatment
Gross description
  • Well circumscribed, resembles lipoma
  • Median 2 cm (range, 1 - 4 cm)
Gross images

Case of the Week #49

Well circumscribed tumor



Images hosted on other servers:

Parotid sialoangiolipoma

Microscopic (histologic) description
  • Mature adipose tissue mixed with acinar, ductal, basal and myoepithelial cells of normal salivary gland
  • Also duct ectasia with fibrosis, prominent lymphoid infiltrates with nodular aggregates in stroma, oncocytic changes, sebaceous differentiation
  • Vascular variant is sialoangiolipoma
Microscopic (histologic) images

Case of the Week #49

Peripheral
lipomatous tissue
with central salivary
gland elements

Lipoma-like areas

Acini and dilated ducts


Ducts with fibrosis of wall infiltrated by lymphocytes



Images hosted on other servers:

Lower lip tumor

Submandibular sialoangiolipoma

Parotid sialoangiolipoma

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