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Definition / general | Terminology | Epidemiology | Clinical features | Clinical images | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Eosinophilic pustular folliculitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumoreosinophilicpustularfolliculitis.html. Accessed April 26th, 2018.
Definition / general
- Associated with HIV in US
- Sudden onset of disseminated pustules on trunk
Terminology
- Also called Ofuji disease, eosinophilic folliculitis
Epidemiology
- Typically recurrent disease and spontaneous resolution within months to several years
- Associated with HIV, lymphoma (non Hodgkin and Hodgkin), myelodysplastic syndrome, eosinophilic cellulitis and nevoid basal cell carcinoma syndrome
Clinical features
- Three variants:
- Classic (Ofuji disease)
- Immunosuppression / HIV associated
- Infancy associated
- Clinically resembles acne
- No known cause
Microscopic (histologic) description
- Eosinophilic infiltration of hair follicle; follicular epithelium is spongiotic, adjacent dermis has lymphocytic and eosinophilic infiltrate
- Superficial dermal perivascular mononuclear and eosinophilic infiltrate
- Follicular mucinosis may rarely be seen
- Healing is associated with post-inflammatory hyperpigmentation