Skin-nontumor / Clinical dermatology
Other dermatoses
Eosinophilic pustular folliculitis

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 24 June 2016, last major update July 2011

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PubMed Search: Eosinophilic pustular folliculitis

Cite this page: Eosinophilic pustular folliculitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumoreosinophilicpustularfolliculitis.html. Accessed April 27th, 2017.
Definition / general
  • Associated with HIV in US
  • Sudden onset of disseminated pustules on trunk
Terminology
  • Also called Ofuji disease, eosinophilic folliculitis
Epidemiology
  • Typically recurrent disease and spontaneous resolution within months to several years
  • Associated with HIV, lymphoma (non Hodgkin and Hodgkin), myelodysplastic syndrome, eosinophilic cellulitis and nevoid basal cell carcinoma syndrome
Clinical features
  • Three variants:
    • Classic (Ofuji disease)
    • Immunosuppression / HIV associated
    • Infancy associated

  • Clinically resembles acne
  • No known cause
Clinical images

Images hosted on other servers:

Widespread hyperpigmented patches

Various images

Microscopic (histologic) description
  • Eosinophilic infiltration of hair follicle; follicular epithelium is spongiotic, adjacent dermis has lymphocytic and eosinophilic infiltrate
  • Superficial dermal perivascular mononuclear and eosinophilic infiltrate
  • Follicular mucinosis may rarely be seen
  • Healing is associated with post-inflammatory hyperpigmentation
Microscopic (histologic) images

Images hosted on other servers:

Eosinophilic folliculitis