Eosinophilic pustular folliculitis

Skin inflammatory (nontumor)
Folliculitis, perifolliculitis and disease of skin appendages
Eosinophilic pustular folliculitis

Author: Mowafak Hamodat, M.B.Ch.B., M.Sc.

Topic Completed: 1 July 2011

Revised: 29 March 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Eosinophilic pustular folliculitis

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Table of Contents

Cite this page: Hamodat M Eosinophilic pustular folliculitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumoreosinophilicpustularfolliculitis.html. Accessed June 17th, 2019.

Definition / general

Associated with HIV in U.S.
Sudden onset of disseminated pustules on trunk

Terminology

Also called Ofuji disease, eosinophilic folliculitis

Epidemiology

Typically recurrent disease and spontaneous resolution within months to several years
Associated with HIV, lymphoma (non-Hodgkin and Hodgkin), myelodysplastic syndrome, eosinophilic cellulitis and nevoid basal cell carcinoma syndrome

Clinical features

Three variants:
- Classic (Ofuji disease)
- Immunosuppression / HIV associated
- Infancy associated
Clinically resembles acne
No known cause

Clinical images

Images hosted on other servers:

Widespread hyperpigmented patches

Various images

Microscopic (histologic) description

Eosinophilic infiltration of hair follicle; follicular epithelium is spongiotic, adjacent dermis has lymphocytic and eosinophilic infiltrate
Superficial dermal perivascular mononuclear and eosinophilic infiltrate
Follicular mucinosis may rarely be seen
Healing is associated with postinflammatory hyperpigmentation

Microscopic (histologic) images

Images hosted on other servers:

Eosinophilic folliculitis