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Skin-nontumor / Clinical Dermatology

Granulomatous but non-infectious disorders

Foreign body reaction


Reviewer: Mowafak Hamodat, MB.CH.B, MSc., FRCPC (see Reviewers page)
Revised: 25 August 2011, last major update July 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Due to talc, silicon, lipid, zirconium, beryllium, prior surgery or arthropod bites, tattoos, keratin or urates
● May occur rarely due to skin adhesives (Arch Orthop Trauma Surg 2009;129:167)
● All may cause granulomatous reactions

Micro description
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● Polarizing microscope demonstrates talc, silica, lipids
● Beryllium is associated with necrotizing and granulomatous reaction

Micro images
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Post-surgical foreign body reaction due to suture material

   
Due to wooden foreign body, tattoo pigment

End of Skin-nontumor / Clinical Dermatology > Granulomatous but non-infectious disorders > Foreign body reaction


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