Skin - nontumor / clinical dermatology
Other dermatoses
Gyrate erythema

Author: Mowafak Hamodat, M.D., M.Sc. (see Authors page)

Revised: 4 September 2018, last major update July 2011

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Gyrate erythema

Cite this page: Hamodat, M. Gyrate erythema. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumorgyrateerythema.html. Accessed September 25th, 2018.
Definition / general
  • Various erytematous eruptions with a curvilinear ("gyrate") appearance:
  • Erythema annulare centrifugum: most common gyrate erythema, but etiology unknown; may grow over weeks, resolves in 1 - 2 months
  • Erythema marginatum rheumaticum: due to rheumatic fever, now extremely rare
  • Erythema gyratum repens: uncommon, paraneoplastic process associated with internal malignancy (eMedicine)
  • Erythema chronicum migrans: occurs after a tick bite, may be associated with Lyme disease (Wikipedia)
Terminology
  • Also called figurate erythema
Case reports
  • 64 year old woman with pruritic, erythematous plaques on abdomen and back that appeared and disappeared (Case of the Week #71)
Clinical features
  • Multiple waves of curvilinear erythema and scale
  • Rash may migrate and be pruritic
Clinical images

Images hosted on other servers:

Erythema annulare centrifugum - pregnant woman

Erythema gyratum repens

Erythema marginatum rheumaticum

Erythema chronicum migrans

Microscopic (histologic) description
  • Nonspecific changes
  • Dense perivascular lymphocytic infiltrate of superficial dermis and possibly deep reticular dermis
  • Lymphocytes are well demarcated and adjacent to vessels ("coat sleeve" or "pipe stem" appearance in erythem annulare centrifugum)
  • Variable epidermal spongiosis, mild ancanthosis and parakeratosis; may have focal vacuolar changes
Microscopic (histologic) images

Images hosted on PathOut server:

Case of the Week #71:

Erythema gyrated repent



Images hosted on other servers:

Erythema annulare centrifugum - pregnant woman

Erythema chronicum migrans

Positive stains
  • Erythema gyratum repens: occasional presence of C3, C4 and IgG at the basement membrane zone with direct immunofluorescence