Skin-nontumor / Clinical Dermatology
Reviewer: Mowafak Hamodat MB.CH.B, MSc., FRCPC, Memorial University of Newfoundland (see Reviewers page)
Revised: 24 August 2011, last major update August 2010
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.
● Bone marrow derived dendritic cells that present antigens to T cells
● Scattered in upper squamous layer and in the dermis, but difficult to see on H&E
S100+ cells in skin
● S100, CD1a; also IgG Fc receptor, C3
● Have characteristic Birbeck granules (rod shaped structure with zipper-like striations, often with bulbous end)
Electron microscopy images
American Academy of Dermatology
End of Skin-nontumor / Clinical Dermatology > General > Langerhans cells
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