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Skin-nontumor

Other dermatoses

Lichenoid dermatitis


Reviewer: Mowafak Hamodat MB.CH.B, MSc., FRCPC, Eastern Health, St. Johns (Canada) (see Reviewers page)
Revised: 1 August 2011, last major update August 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● A histological pattern, not a distinct clinical entity
● Due to drug eruption, actinic keratosis, lupus erythematosus, acute graft versus host disease, regressing melanoma and dermatofibroma
● May be a delayed hypersensitivity reaction
● May present as a neoplasm

Micro description
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● Dense, bandlike lymphocytic infiltrate in dermis that obscures dermoepidermal junction
● Cytoplasmic vacuolization of basal keratinocytes with a brightly eosinophilic cytoplasm; the nucleus becomes extruded to become round/oval eosinophilic bodies (colloid bodies)
● Regenerated epithelium has a disorderly basement membrane
● May have large cell acanthoma or solar lentigo within the lesion

End of Skin-nontumor > Other dermatoses > Lichenoid dermatitis


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