Skin nontumor
Psoriasiform dermatoses
Lichen simplex chronicus

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 26 May 2017, last major update August 2011

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Lichen simplex chronicus [title]

Cite this page: Lichen simplex chronicus. website. Accessed September 24th, 2018.
Definition / general
  • Plaque like condition due to chronic rubbing and scratching
  • Also called neurodermatitis
Clinical features
  • Thick, scaly plaques with erythema, well demarcated from surrounding skin
  • Associated with excoriation, lichenification, crusting
  • Raised nodules are called prurigo nodularis
Microscopic (histologic) description
  • Marked hyperkeratosis associated with foci of parakeratosis
  • Prominent granular cell layer
  • The epidermal rete are elongated and irregularly thickened
  • Mild spongiosis
  • Perivascular and interstitial inflammation with histiocytes, lymphocytes and occasional eosinophils in superficial dermis
  • Occasionally enlarged elongated myofibroblasts, papillary dermal fibrosis, nerve hyperplasia
Additional references