Skin inflammatory (nontumor)
Merkel cells

Author: Mowafak Hamodat MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 11 October 2018, last major update August 2010

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Merkel cells [title]

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Cite this page: Hamodat, M. Merkel cells. website. Accessed January 21st, 2019.
Definition / general
  • Difficult to see with H&E or special stains
  • Concentrated in skin of digits, finger pads, proximal nail folds, palms, dorsum of feet, lips, hard palate
  • More common in outer root sheath of hair follicles and tactile hair discs
Diagrams / tables

Images hosted on other servers:

Skin and Merkel cells

Positive stains
Electron microscopy description
  • Dense core neurosecretory-type granules in cytoplasm beneath cell membrane or within unmyelinated neurites
  • Anchored to adjacent keratinocytes by spinous processes
Additional references