Skin inflammatory (nontumor)
Infectious disorders
Molluscum contagiosum


Topic Completed: 1 March 2011

Revised: 1 April 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Molluscum contagiosum [title]

Mowafak Hamodat, M.B.Ch.B., M.Sc.
Page views in 2018: 13,521
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Cite this page: Hamodat M Molluscum contagiosum. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumormolluscum.html. Accessed August 18th, 2019.
Definition / general
  • Infectious disorder caused by molluscum contagiosum poxvirus
  • Multiple nodules on skin, trunk or anogenital region, due to skin to skin contact or sexual transmission
Clinical features
  • Multiple firm, pruritic, pink-tan nodules, up to 4 mm, with central cores containing white keratinous material
Clinical images

Contributed by Dr. Mark R. Wick

Breast skin


Images hosted on other servers:

Raised, firm, flesh colored nodules

Microscopic (histologic) description
  • Lobulated endophytic hyperplasia that produces a circumscribed intradermal pseudotumor
  • Molluscum bodies are present (large cells with cytoplasmic, faintly granular eosinophilic inclusions that displace nuclei and contain viral particles); made more conspicuous with Lendrum’s phloxine tartrazine reaction
  • May have intense dermal lymphocytic infiltrate that suggests lymphoma
  • Rarely metaplastic ossification
Microscopic (histologic) images

Contributed by Dr. Mark R. Wick

Breast skin


Contributed by Dr. Julia Braza

Abdominal skin of 29 year old man



Contributed by Dr. Angel Fernandez-Flores, Ph.D.



Contributed by Dr. Mowafak Hamodat



Images hosted on other servers:

H&E

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