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Skin-nontumor / Clinical Dermatology

General

Normal dermis and subcutis


Reviewer: Mowafak Hamodat MB.CH.B, MSc., FRCPC, Memorial University of Newfoundland (see Reviewers page)
Revised: 24 August 2011, last major update August 2010
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Micro description
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● Contains collagen and elastic fibers within ground substance composed of mucopolysaccharides and mucoproteins
● Also contains adnexa, nerves and blood vessels
● Degenerates with age and sunlight and becomes basophilic
● Divided into superficial papillary dermis and deeper reticular dermis
● Papillary dermis contains rete pegs and periadnexal dermis
● Papillary dermis has thin and delicate collagen fibers compared to thicker fibers in reticular dermis
● Dermis has varying degrees of thickness - thicker on back
● Acral skin has Sucquet-Hoyel canals specialized arteriovenous anastomoses, surrounded by glomus cells
● Glomus cells are modified smooth muscle cells that are round with clear cytoplasm and well defined cytoplasmic borders
● Papillary dermis of palms and soles contains Wagner-Meissner corpuscles with a tactile function
● Deep dermis and subcutis of weight bearing areas contain Pacinian corpuscles, sensitive to pressure
● Normal dermis contains a few fibroblasts, mast cells, macrophages, lymphocytes and dermal dendrocytes (Factor XIIIa+)

● Subcutis also called subcutaneous; contains lobules of mature adipose tissue and thin connective tissue septa

End of Skin-nontumor / Clinical Dermatology > General > Normal dermis


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