Skin-nontumor / Clinical dermatology
Other dermatoses
Pityriasis lichenoides et varioliformis acuta

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 20 July 2016, last major update August 2011

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PubMed Search: Pityriasis lichenoides

Cite this page: Pityriasis lichenoides et varioliformis acuta. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skinnontumorpleva.html. Accessed December 9th, 2016.
Definition / General
  • Also called PLEVA, Mucha-Habermann disease
  • Overlaps with pityriasis lichenoides chronica
  • Sudden onset of crops of small, ulcerated papules on trunk
  • May heal with superficial scarring resembling variola (smallpox)
Micro Description
  • Acute lesion shows epidermal changes with much exaggerated scale; marked inter- and intracellular edema accompanied by keratinocyte necrosis and interface changes
  • Exocytosis is usually prominent and intraepidermal red blood cells are characteristic
  • Upper dermis is edematous and contains wedge shape of lymphocytes and histiocytes, usually perivascular, varies from sparse to dense; prominent red cell extravasation
Additional References