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Skin-nontumor / Clinical Dermatology

Other dermatoses

Pityriasis lichenoides et Varioliformis Acuta


Reviewer: Mowafak Hamodat, MB.CH.B, MSc., FRCPC, Eastern Health, St. Johns, Canada (see Reviewers page)
Revised: 1 August 2011, last major update August 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Also called PLEVA, Mucha-Habermann disease
● Overlaps with pityriasis lichenoides chronica
● Sudden onset of crops of small, ulcerated papules on trunk
● May heal with superficial scarring resembling variola (smallpox)

Micro description
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● Acute lesion shows epidermal changes with much exaggerated scale; marked inter- and intracellular edema accompanied by keratinocyte necrosis and interface changes
● Exocytosis is usually prominent and intraepidermal red blood cells are characteristic
● Upper dermis is edematous and contains wedge shape of lymphocytes and histiocytes, usually perivascular, varies from sparse to dense; prominent red cell extravasation

Additional references
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eMedicine

End of Skin-nontumor / Clinical Dermatology > Other dermatoses > Pityriasis lichenoides et Varioliformis Acuta


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