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Skin-nontumor / Clinical Dermatology

Other dermatoses

Spongiotic dermatitis

Reviewer: Mowafak Hamodat, MB.CH.B, MSc., FRCPC, Eastern Health, St. Johns, Canada (see Reviewers page)
Revised: 2 August 2011, last major update August 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Clinically correlates with eczematous dermatitis
● Encompasses a large number of diseases, including allergic contact dermatitis and irritant contact dermatitis

Micro description
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● Intraepidermal edema with clear spaces separating keratinocytes
● Acute: also perivascular lymphocytic infiltrates in upper dermis, lymphocyte exocytosis
● Subacute: focal parakeratosis, acanthosis, papillomatosis, eosinophils
● Chronic: prominent parakeratosis, acanthosis, papillomatosis; may have minimal spongiosis; fibroplasia of papillary and upper reticular dermis; variable inflammatory infiltrate

Micro images
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Spongiotic dermatitis

Differential diagnosis
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● Early cutaneous T cell lymphoma: large numbers of cerebriform nuclei, Pautrier’s microabscesses, epidermotropism

End of Skin-nontumor / Clinical Dermatology > Other dermatoses > Spongiotic dermatitis

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