Skin inflammatory (nontumor)
Other dermatoses
Synovial metaplasia

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 22 October 2018, last major update August 2011

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Synovial metaplasia

Cite this page: Hamodat, M. Synovial metaplasia. website. Accessed December 12th, 2018.
Definition / general
  • Metaplastic changes resembling synovium in non-joint spaces, usually in patients with prior surgery or traumatic injuries
  • Synovial-type membranes may form against surface of suture material, tissue expanders or implants
  • Associated with movement, loose areolar tissue that would develop spaces secondary to movement, and relatively smooth gliding surfaces that can resist penetration by fibroblasts (Arch Pathol Lab Med 2002;126:727)
  • Membranes resemble joint (“true”) synovial membranes
  • May be associated with cyst formation and transepidermal fistulae (Am J Surg Pathol 1987;11:343)
Clinical features
  • Resemble suture granulomas
Microscopic (histologic) description
  • Resembles hyperplastic synovium
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
Negative stains