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Table of Contents
Clinical Features | Clinical Images | Micro Description | Micro Images | Positive StainsClinical Features
- Secondary lesions occur on face and trunk; are maculopapular and resemble drug eruption, lichen planus and psoriasis
- May present as moth-eaten alopecia on scalp, mucous patches on tongue
- Diagnose by serology
- Scaly, flesh-colored to erythematous papules or annular plaques
- Copper macules on palms and soles
Clinical Images
Images hosted on PathOut servers:
Secondary, courtesy of Dr. Mark R. Wick
Gumma, courtesy of Dr. Mark R. Wick
Micro Description
- Dense perivascular or diffuse plasma cell infiltrate with marked endothelial swelling and proliferation in blood vessels
- May have noncaseating granulomas, vacuolar interface change, acanthosis, spongiosis or lymphocyte exocytosis
Micro Images
Images hosted on PathOut servers:
Secondary, breast skin, courtesy of Dr. Mark R. Wick
Steiner stain, secondary, courtesy of Dr. Mark R. Wick
Gumma, breast, courtesy of Dr. Mark R. Wick
Images hosted on other servers:
Primary syphilis
Positive Stains
- Steiner stain (71% sensitive)
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