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Skin-Melanocytic Tumors
Ito’s nevus
Last major update: November 2008 - next update November 2009
Revised: 28 June 2009
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Copyright: (c) 2002-2009, PathologyOutlines.com, Inc.
Definition
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● First described by Minor Ito in 1954 (Tohoko J Exper Med. 1954;60:10)
Epidemiology
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● Usually affects Orientals, also Hispanics, blacks, Native Americans
● Different entity from Hypomelanosis of Ito, a neurocutaneous disorder (J Child Neurol 2000;15:635)
● Often occurs with nevus of Ota in same patient, but is much less common
Clinical
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● Similar to nevus of Ota except for location; Ito’s nevus is found in shoulder, side of neck and supraclavicular areas, within the distribution of the lateral (also called posterior) supraclavicular nerve and lateral cutaneous brachial nerves; nevus of Ota is found around the eyes
Case reports
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● With nevus of Ota (Indian J Dermatol Venereol Leprol 2004;70:112)
Treatment
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● Laser to lighten pigment (cosmetic purposes)
Clinical description
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● Macule with irregular blue-gray pigmentation
Clinical images
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Shoulder lesions Nevus of Ota (face) and
nevus of Ito (shoulder)
Micro description
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● Deeply pigmented dendritic melanocytes and melanophages dissecting bundles of dermal collagen in reticular dermis
● Overlying epidermis is normal
Additional references
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End of Skin-Melanocytic Tumors > Ito’s nevus
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