Atypical melanocytic hyperplasia
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Revised: 26 October 2009, last major update November 2008
Copyright: (c) 2005-2009, PathologyOutlines.com, Inc.
● Controversial topic
● Associated with esophageal squamous cell carcinoma in situ (Virchows Arch 2000;437:203)
● Atypical single unit melanocytes limited to epidermis, often seen at periphery of classic melanoma
● As opposed to melanoma in situ, exhibit only focal confluence at the dermoepidermal junction, limited pagetoid spread and involvement of only the upper part of the hair follicles
Benign atypical junctional melanocytic hyperplasia
● Melanoma in situ (Am J Dermatopathol 1996;18:560)
End of Skin-Melanocytic Tumors > Atypical melanocytic hyperplasia
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