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Skin-Melanocytic tumors
Linear and whorled nevoid hypermelanosis
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Revised: 5 July 2009, last major update November 2008
Copyright: (c) 2005-2009, PathologyOutlines.com, Inc.
Definition
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● Rare skin disorder, often in first weeks of life, with swirls and streaks of macular hyperpigmentation along lines of Blaschko
● Usually not associated with other abnormalities (Pediatr Dermatol 2007;24:205)
Case reports
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● 20 year old man with widespread involvement associated with scoliosis, unsuccessfully treated with medium depth chemical peel (Dermatol Online J 2007;13(3):23)
● Familial cases (J Am Acad Dermatol 1994;30:831)
Treatment and prognosis
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● No satisfactory treatment
Clinical description
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● Swirls and whorls of hyperpigmented macules in reticulate pattern along Blaschko's lines (Wikipedia, image)
Clinical images
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Hyperpigmented streaks show whorled pattern over the trunk; no improvement after medium-depth chemical peel regimen applied to rectangular area
Micro description
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● Epidermal melanosis
● No pigment incontinence or melanophages
Micro images
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Diffuse melanosis of basal layer of epidermis
End of Skin-Melanocytic Tumors > Linear and whorled nevoid hypermelanosis
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