Skin-melanocytic tumor
Ito’s nevus

Author: Christopher Hale, M.D. (see Authors page)

Revised: 21 February 2017, last major update April 2013

Copyright: (c) 2003-2017,, Inc.

PubMed Search: Nevus of Ito [title]
Cite this page: Itos nevus. website. Accessed November 17th, 2018.
Definition / general
  • First described by Minor Ito in 1954 (Tohoko J Exper Med. 1954;60:10)
  • More accurately grouped with "dermal melanocytoses" (nevus of Ito, nevus of Ota, Hori nevus, so-called "Mongolian" spot) (eMedicine - Nevi of Ota and Ito)
  • Although melanocytic, it is NOT a true nevus
  • Different entity from Hypomelanosis of Ito, a neurocutaneous disorder (J Child Neurol 2000;15:635)
  • Usually individuals with pigmented skin, most commonly Asians; also Hispanics, blacks, Native Americans
  • More common in women
  • Often occurs with nevus of Ota in same patient, but is much less common
  • By definition, found in "shawl" or "cloak" distribution
Clinical features
  • Macule with irregular blue-gray pigmentation
  • Similar to nevus of Ota except for location
  • Ito’s nevus is found in shoulder, side of neck and supraclavicular areas, within the distribution of the lateral (also called posterior) supraclavicular nerve and lateral cutaneous brachial nerves
  • Nevus of Ota is found around the eyes
Case reports
Clinical images

Images hosted on other servers:
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Shoulder lesions

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Nevus of Ota (face) and nevus of Ito (shoulder)

Microscopic (histologic) description
  • Deeply pigmented dendritic melanocytes and melanophages dissecting bundles of dermal collagen in reticular dermis
  • Overlying epidermis is normal