Skin-melanocytic tumor
Nevi
Deep penetrating nevus

Author: Christopher Hale, M.D. (see Authors page)

Revised: 1 February 2017, last major update June 2014

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: deep penetrating nevus [title]
Cite this page: Deep penetrating nevus. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumormelanocyticdeeppennevus.html. Accessed February 28th, 2017.
Definition / General
  • Very cellular melanocytic nevus consisting of spindled melanocytes extending into reticular dermis or subcutis (Arch Dermatol 1993;129:328)
Terminology
Epidemiology
Sites
Clinical Features
Case Reports
Treatment
Clinical Images

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Linear distribution of nevi behind ear

Micro Description
  • Nevus whose dermal component extends into reticular dermis or subcutis
  • Cellular, nested or fascicular with abundant pigment and mild atypia
  • Usually inconspicuous junctional component
  • Plump regular nests of melanocytes in dermis
  • Mild cytologic atypia with some nuclear pleomorphism, small to medium-sized eosinophilic nucleolus (Arch Pathol Lab Med 2011;135:321)
  • Occasional normal dermal mitotic figures, patchy mononuclear inflammatory cell infiltrate
  • Absence of maturation
  • May be combined with other nevi
Micro Images

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Breast skin, courtesy of Dr. Mark R. Wick



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Various images

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H&E

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Various images

Differential Diagnosis